Adverse Drug Events Reporting News

• High Dose Atropine Curbs Myopia in Kids Despite Side Effects Children with myopia receiving 0.05% atropine showed less progression of the eye condition and axial elongation than those receiving placebo, according to 3-year results of the MOSAIC trial.
  Medscape Medical News, January 10, 2025
• What’s the Best Approach for Sustained Weight Loss? With nutritional, pharmaceutical, and surgical options available for obesity, clinicians are being called upon to make decisions about how to best help their patients lose weight and keep it off.
  Medscape Medical News, January 10, 2025
• Are Patients On GLP-1s Getting the Right Nutrients? As GLP-1 RA use soars, experts are worried that patients may not be getting the right nutrients in their diets. How can clinicians support their patients’ nutritional needs?
  Medscape Medical News, January 10, 2025
• Do Antibiotics Before Conception Affect Fertility? An expert cautions against misinterpretation of a meta-analysis linking preconception antibiotics to infertility and pregnancy complications.
  Medscape Medical News, January 09, 2025
• Intensive BP Control May Benefit CKD Patients in Real World Intensive blood pressure control in patients with chronic kidney disease showed cardiovascular benefits in real-world settings similar to those observed in the SPRINT.
  Medscape Medical News, January 07, 2025
• Retatrutide Produces Greatest Weight Loss Dual- and triple-agonist GLP-1s appear to achieve greater weight loss in an overview of clinical trials of approved and investigational agents.
  Medscape Medical News, January 07, 2025
• Donepezil Shows Promise in TBI Recovery Donepezil was associated with improved verbal memory and processing speed compared to placebo in patients with TBI and severe, persistent impairments.
  Medscape Medical News, January 07, 2025
• Docs Worry Not Enough Known About GLP-1s and Teens Eighty percent of doctors in a Medscape survey answered no when asked, “Is enough known about obesity meds’ risk to adolescents?”
  Medscape Medical News, January 02, 2025
• Panel Offers Best Practice Statement for Microbiota Testing International experts who convened to regulate the “wild west” of currently available diagnostic tests found little evidence to support their use in clinical practice.
  Medscape Medical News, December 31, 2024
• MRI-Guided SBRT Cuts Long-Term Toxicities in Prostate Cancer The MIRAGE trial highlighted how MRI-guided stereotactic body radiotherapy with tight margins can reduce the long-term side effects of radiotherapy in men with localized prostate cancer.
  Medscape Medical News, December 30, 2024
• Expert Tips for Managing GLP-1 Medication Side Effects Experts say patients should adjust dosage, try prescribed and over-the-counter drugs to help with symptom management and dietary changes to deal with side effects.
  Medscape Medical News, December 27, 2024
• Adverse Events Risk Differs Among Men and Women With MASLD Serious liver and nonliver outcomes linked to metabolic dysfunction–associated steatotic liver disease were different between men and women, according to the first known study to examine this topic.
  Medscape Medical News, December 26, 2024
• Should the FDA Reconsider Antidepressant Boxed Warnings? For nearly 20 years, antidepressants have carried suicide risk warnings for young people. Now, experts are questioning if the FDA should reconsider these warning labels.
  Medscape Medical News, December 23, 2024
• MMRV Safety Assessed in Children on Methotrexate, Dupilumab No adverse events were observed in a small retrospective study of pediatric patients receiving the MMRV vaccine while on dupilumab or methotrexate.
  Medscape Medical News, December 20, 2024
• New Guidance Backs Metformin for Antipsychotic Weight Gain A new guideline recommends prescribing metformin when initiating an antipsychotic to help mitigate weight gain in certain instances.
  Medscape Medical News, December 20, 2024
• A New Weight Loss Drug With No Side Effects? Yes…So Far Researchers have achieved impressive results in animal studies with a new weight-loss drug that has no GLP-1-style side effects — especially muscle loss.
  Medscape Medical News, December 18, 2024
• Novo's Ozempic Faces Scrutiny Over Potential Link to Rare Eye Disease Danish health authorities said on Monday they would ask the European Union's drug regulator to review the findings of two Danish studies linking Novo Nordisk's popular...
  Reuters Health Information, December 16, 2024
• CAR-T Cells and Beyond: Breakthroughs and Challenges Ahead Six CAR-T-cell therapies have been approved by the European Commission and the US FDA, and other T-cell therapies are being developed.
  Medscape Medical News, December 16, 2024
• MSWS 2024 Integrative Dermatology Addresses Unmet Need When managing complex chronic dermatologic diseases, efforts to incorporate alternative treatments can add efficacy, patient reassurance, and patient engagement.
  Medscape Medical News, December 15, 2024
• Alert Rytelo Recommended in Europe for Myelodysplastic Syndromes This drug reduces the malignant clones that crowd out healthy blood cells in the bone marrow.
  Medscape Medical News, December 13, 2024