Inflammatory Bowel Disease News

• Noninvasive Microbiome Test May Identify Crohn’s and UC Researchers have uncovered potentially diagnostic gut microbiome signatures and metabolic pathways associated specifically with ulcerative colitis and Crohn’s disease.
  Medscape Medical News, December 19, 2024
• Alert FDA Approves Seventh Ustekinumab Biosimilar, Steqeyma Ustekinumab-stba, manufactured by Celltrion, is expected to be marketed in the United States in February 2025.
  Medscape Medical News, December 19, 2024
• Teva, Sanofi Say Bowel Disease Drug Met Primary Targets (Dec 17) (This Dec.17 story has been corrected to say the results were for ulcerative colitis, not for both the diseases, in paragraph 5)
  Reuters Health Information, December 17, 2024
• How Exactly Does One Map the Human Gut? As part of the ongoing Human Cell Atlas project, researchers mapped 1.6 million cells in the gastrointestinal tract. Here’s how they pulled it off — and what it means.
  Medscape Medical News, December 17, 2024
• Abdominal Pain Common in Both Active and Quiescent UC In a multicohort study, abdominal pain was found to be common in patients with ulcerative colitis, regardless of whether they had an active disease or were in deep remission.
  Medscape Medical News, December 13, 2024
• Higher Risk for Herpes Zoster Complications With IBD Patients with IBD were more likely to have complications of herpes zoster than those without IBD, highlighting the importance of vaccination in this population.
  Medscape Medical News, December 06, 2024
• GLP-1s Boost IBD Outcomes in Patients With T2D and Obesity The use of GLP-1s is linked to improved inflammatory bowel disease outcomes in patients with concomitant inflammatory bowel disease and type 2 diabetes, specifically in those with obesity.
  Medscape Medical News, December 06, 2024
• Inflammation Predicts Increased Fracture Risk in IBD Controlling intestinal inflammation for 12-month periods reduced fracture risk in patients with inflammatory bowel disease, according to a nationwide Swedish study.
  Medscape Medical News, December 05, 2024
• Alert FDA Approves Ustekinumab Biosimilar Yesintek This is the sixth ustekinumab biosimilar approval in the United States, with the drug set to launch in 2025.
  Medscape Medical News, December 03, 2024
• Guidelines Endorse Earlier Use of High-Efficacy Drugs for UC The American Gastroenterological Association has issued updated practice guidelines for the pharmacological management of moderate to severe ulcerative colitis in adults.
  Medscape Medical News, November 25, 2024
• Anti-TNF Therapy Lowers Gestational Diabetes Risk in IBD Anti-TNF therapy during the early stages of pregnancy was associated with a decrease in the risk for gestational diabetes among women with inflammatory bowel disease.
  Medscape Medical News, November 22, 2024
• Long-Term Risk for Some Skin Disorders Increased After COVID A study using a Korean database found that COVID-19 infection raised long-term risks for various autoimmune and autoinflammatory skin disorders, and vaccination may reduce these risks.
  Medscape Medical News, November 20, 2024
• ACG 2024 JAK Inhibitors Vs Anti-TNF: No Increased Risk of MACE in IBD Patients with IBD don’t face an increased risk for major adverse cardiovascular events when taking Janus kinase inhibitors compared with anti-TNF agents.
  Medscape Medical News, November 19, 2024
• Aggressive Infliximab Dosing Shows No Added Benefit in UC Aggressive infliximab dosing did not provide additional clinical benefits for patients with steroid-refractory acute severe ulcerative colitis compared with standard dosing.
  Medscape Medical News, November 19, 2024
• ACG 2024 FMT With Bezlotoxumab in IBD Patients With Recurrent CDI A randomized controlled trial finds no clear benefit of adding bezlotoxumab to FMT in patients with IBD and recurrent C difficile infection.
  Medscape Medical News, November 11, 2024
• UEG 2024 Patients With IBD More Likely to Develop, or Have Prior, T1D A bidirectional relationship exists between inflammatory bowel disease and type 1 diabetes, which warrants heightened awareness to facilitate earlier detection of both diseases.
  Medscape Medical News, October 18, 2024
• UEG 2024 Genetic Marker Tied to Severe Ulcerative Colitis Identified The HLA-DRB1*01:03 allele was significantly associated with increased severity of ulcerative colitis, including higher rates of hospitalization, surgery, and corticosteroid use.
  Medscape Medical News, October 17, 2024
• UEG 2024 UPFs Associated With Relapse Risk in Crohn’s Disease A diet high in ultraprocessed foods can raise the relapse risk in patients with Crohn’s disease who are in remission, with some subgroups of those foods increasing that risk approximately threefold.
  Medscape Medical News, October 17, 2024
• Live Rotavirus Vax Safe for Babies of Biologic-Treated Moms Evidence suggested there is little risk in administering the live rotavirus vaccine to the babies of mothers on biologics during pregnancy for inflammatory bowel disease.
  Medscape Medical News, October 11, 2024
• Review Highlights GI Risks for Biologic Rxs for Psoriasis Interleukin-17 inhibitors showed a higher relative risk for GI events, in a review.
  Medscape Medical News, October 09, 2024